10/24/2018 / By Ellaine Castillo
A group of researchers from the University of Peshawar and the Cardiff School of Pharmacy and Pharmaceutical Sciences revealed that the purple passionflower (Passiflora incarnata) has potential use as a treatment for neuropathic pain. Their study, which was published in BMC Complementary and Alternative Medicine, looked at the pain-relieving effects of purple passionflower extracts on rodents with streptozotocin-induced diabetic neuropathy.
Results of the study showed that the purple passion flower effectively relieves pain through a mechanism that involves opioids and gamma-aminobutyric acid (GABA). In addition to this, GABA was involved in reducing anxiety and inducing sedation. Lastly, the purple passionflower extracts also exhibited anti-allodynic and anti-vulvodynia effects. Overall, these results prove that the purple passionflower has potential use for treating neuropathic pain.
Read the full text of the study at this link.
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Journal Reference:
Aman U, Subhan F, Shahid M, Akbar S, Ahmad N, Ali G, Fawad K, Sewell RDE. PASSIFLORA INCARNATA ATTENUATION OF NEUROPATHIC ALLODYNIA AND VULVODYNIA APROPOS GABA-ERGIC AND OPIOIDERGIC ANTINOCICEPTIVE AND BEHAVIOURAL MECHANISMS. BMC Complementary and Alternative Medicine. 24 February 2016;16(77). DOI: 10.1186/s12906-016-1048-6
Tagged Under: antinociceptive, diabetic neuropathy, GABA, gamma-Aminobutyric acid, herbal medicine, nerves, nervous system, neuropathic pain, nociceptive, pain, pain relief, Passiflora Incarnata, purple passionflower, traditional medicine